Dr.Prasenjit Kalita

Dr.IKU DUTT, Dr.Nripendra Kumar Bora

Abstract

INTRODUCTION-HYPOPYON DEVELOPED IN MORE THAN 50% OF SEVERE FUNGAL CORNEAL ULCER.IT REQUIRES TIMELY DIAGNOSIS AND ADMINISTRATION OF APPROPRIATE ANTIFUNGAL THERAPY.AIM-TO STUDY THE CHANGES OF HYPOPYON IN FUNGAL CORNEAL ULCER WITH TOPICAL VORICONAZOLE AND NATAMYCIN .MATERIALS & METHODS-PRESENT STUDY WAS CARRIED OUT IN A TERTIARY CARE HOSPITAL FROM JAN 19 TO DEC 19 WITH 40 PATIENT WITH FUNGAL CORNEAL ULCER.RESULTS-TWO GROUPS WITH 20 PATIENTS RECEIVED EITHER TOPICAL VORICONAZOLE OR NATAMYCIN .HYPOPYON PRESENT IN 13&11 PATIENTS IN VORICONAZOLE &NATAMYCIN GROUP.MEAN HEIGHT OF HYPOPYON IN PATIENTS WHO RESPONDS TO Rx AT 4 WEEK WAS 0.15+0.20mm AND 0.10+0.12mm IN EACH GROUP.CHANGE IN MEAN HEIGHTS OF HYPOPYON AT SUBSEQUENT FOLLOW UP WAS SIGNIFICANT.CONCLUSION-HYPOPYON PRESENT IN FUNGAL CORNEAL ULCER RESPOND WELL TO TOPICAL VORICONAZOLE AND NATAMYCIN .CHANGE OF MEAN HEIGHT OF HYPOPYON IN FOLLOW UP IS SIGNIFICANT.