Dr. LIPI CHAKRABARTY

Abstract

AIM:To analyze rise in intraocular pressure(IOP) with the use of topical difluprednate 0.05% ophthalmic emulsion(DFBA)

METHOD:Hospital based,prospective,observational cohort study done over 7mths. Involved 150 nonglaucomatous eyes of consenting,inclusion-eligible adults of uncomplicated cataract.Eyes got operated by same surgeon.Postop,DFBA was started as 4 times,tapered over 4 weeks. IOP taken preop,2days postop and at 1st, 2nd and 3rd review till 5th postop week.Descriptive statistics,paired t-test,chi square test used

RESULT:In 138 patients(12 excluded) with average age of 66.4 ± 6.89years, 64% were males and 36% females. Average baseline IOP: 14.4±2.43mmHg. Rise in IOP above 20mmHg found in 9 eyes(6.5%). Of these, 2 had IOP rise 5mmHg above baseline(>20%). IOP managed by discontinuation of DFBA. No association of IOP rise with age,gender,laterality of eye, diabetes

CONCLUSION:Eyes on DFBA to be followed regularly with IOP monitoring.Strength:Robust sample size, prospective design.