Dr. DEEPAK MISHRA

Dr.Mahendra Kumar Singh, DR. TANMAY SRIVASTAV, Dr. HEMENDRA SINGH

Abstract

AIM: To assess the relationship between macular thickness as characterized by optical coherence tomography (OCT) and risk factor (serum lipid) for diabetic retinopathy (DR) in type 2 diabetic patients with no DME.

METHODS: A hospital based study carried out for a period of 11 months. A total of 98 patients with type 2 diabetes without DME were taken. Central macular thickness was measured using spectral-domain OCT. Association between OCT parameters and known risk factor(serum lipid) for DR were examined.

RESULTS:A total of 98 patients were included in our study among which 58%were males. The mean CMT value was 283.6 micron. After adjusting for age, sex, duration of diabetes, hemoglobinA1c and urineprotein, low-density lipoprotein (LDL) cholesterol was positively associated with CSMT; each 1 mmol/L increase in LDL was associated with a mean increase in CSMT of 7.14 micron.

CONCLUSION: A higher LDL cholesterol level was associated with increased CSMT indiabetics without DME.