Dr. Ghanta Divya

Dr. R. SURYANARAYANA RAJU

Abstract

Diabetic Retinopathy (DR) is one of the leading causes of low vision and blindness. Recently homocysteine is postulated as risk factor for diabetic retinopathy . Aim of the study is to evaluate the association of homocysteine with diabetic retinopathy .

Methodology

200 diabetic patients 100 with diabetic retinopathy and 100 without diabetic retinopathy fulfilling the criteria were selected. Base line investigations and fasting serum homocysteine levels were assessed. Demographic data and risk factors were documented.

Results

Mean plasma homocysteine levels in PDR group (26.54 μmol/l) were higher than NPDR (18.96 μmol/l) and No DR group(13.98 μmol/l).Higher prevalence of hyperhomocysteinemia was seen in PDR group.Higher BMI ,anaemia ,poor glycemic control ,high cholestrol and high serum homocysteine levels seen in PDR group compared to other groups.