DR. MARIAN HANSIE

Dr. RADHIKA THUNDIKANDY

Abstract

BACKGROUND: CNVM is a well documented sight threatening complication of posterior segment intraocular inflammation (PSII)

CASE REPORT: A 60years female Mrs.Sujatha came with defective vision in left eye(6/36) since 1month and diagnosed as left eye posterior uveitis due to sarcoidosis with inflammatory CNVM. Systemic evaluation revealed elevated serumACE and CT thorax confirmatory of sarcoidosis. Patient was treated with inj.avastin and oral steroids. After 6months patient came with similar complaints in same eye and diagnosed as active CNVM and inj.avastin given intravitreal. With monthly follow up and 5 injections of avastin ,CNVM did not regress . Patient was then started on immunosuppressant -methotrexate followed by inj.avastin after which it regressed with vision 6/9 LE

CONCLUSION: when CNVM is refractory to repeated invitreal injections and oral steroids, underlying inflammatory component should be treated additionaly with an immunosuppressant for a good visual outcome.